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Aproven General Information

Aproven is used to control and prevent symptoms (wheezing and shortness of breath) caused by ongoing lung disease (chronic obstructive pulmonary disease-COPD which includes bronchitis and emphysema). Aproven works by relaxing the muscles around the airways so that they open up and you can breathe more easily. Controlling symptoms of breathing problems can decrease time lost from work or school.

For preventing symptoms of lung disease, Aproven must be used regularly to be effective. Use your quick-relief inhaler (such as albuterol, also called salbutamol in some countries) for wheezing or sudden shortness of breath unless otherwise directed by your doctor. Aproven does not work as fast as your quick-relief inhaler, but may sometimes be used to relieve symptoms of wheezing or sudden shortness of breath if so prescribed by your doctor.

OTHER USES: This section contains uses of Aproven that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use Aproven for a condition that is listed in this section only if it has been so prescribed by your health care professional.

Aproven may also be used to prevent symptoms of asthma or to treat wheezing or sudden shortness of breath.

How to Use Aproven

Read the Patient Information Leaflet if available from your pharmacist before you start using Aproven and each time you get a refill. Learn how to use this inhaler properly. If you have any questions, ask your doctor or pharmacist.

Follow the instructions for priming the inhaler if you are using it for the first time or if you have not used it for more than 3 days. When priming the inhaler, make sure to spray away from the face so that you do not get the medication into your eyes.

Inhale Aproven by mouth as directed by your doctor, usually 4 times a day. Avoid getting Aproven into your eyes. Aproven may cause eye pain/irritation, temporary blurred vision, and other vision changes. Therefore, when using the inhaler, put your lips tightly around the mouthpiece and keep your eyes closed.

If your prescribed dose is 2 puffs, wait at least one minute between them. If you are using other inhalers at the same time, wait at least 1 minute between the use of each medication.

Rinse your mouth after using the inhaler to prevent dry mouth and throat irritation.

Dosage is based on your medical condition and response to treatment.

Clean the mouthpiece of the inhaler once a week with water. Allow to air-dry fully before using again.

If you are directed to use Aproven regularly, it works best if used at evenly spaced intervals. To help you remember, use it at the same times each day. Do not increase your dose, use Aproven more frequently, or stop using it without first consulting your doctor.

Keep track of the number of inhalations you use, and throw away the canister after you have used the labeled number of inhalations on the package.

Tell your doctor if your symptoms do not improve or if they worsen.

Learn which of your inhalers you should use every day (controller drugs) and which you should use if your breathing suddenly worsens (quick-relief drugs). Ask your doctor ahead of time what you should do if you have new or worsening cough or shortness of breath, wheezing, increased sputum, worsening peak flow meter readings, waking up at night with trouble breathing, if you use your quick-relief inhaler more often (more than 2 days a week), or if your quick-relief inhaler does not seem to be working well. Learn when you can treat sudden breathing problems by yourself and when you must get medical help right away.

Aproven Possible Side Effects

Dizziness, nausea, stomach upset, dry mouth, or constipation may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed Aproven because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Aproven do not have serious side effects.

Infrequently, Aproven may cause severe sudden worsening of breathing problems right after use. If you have sudden worsening of breathing, use your quick-relief inhaler and get medical help right away.

Tell your doctor right away if you have any serious side effects, including: fast/pounding heartbeat, difficult/painful urination.

Get medical help right away if you have any very serious side effects, including: eye pain/swelling/redness, vision changes (such as seeing rainbows around lights at night, blurred vision).

A very serious allergic reaction to Aproven is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Aproven Precautions

Before using Aproven, tell your doctor or pharmacist if you are allergic to it or tiotropium; or to atropine or other belladonna-type drugs; or if you have any other allergies. Aproven may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using Aproven, tell your doctor or pharmacist your medical history, especially of: personal or family history of glaucoma (angle-closure type), difficulty urinating (for example, due to enlarged prostate).

Aproven may make you dizzy or cause blurred vision or other vision changes. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of Aproven, especially problems urinating or constipation.

During pregnancy, Aproven should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if Aproven passes into breast milk. Consult your doctor before breast-feeding.

Aproven Possible Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

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